Mikhail Valivach. Long-Term Human Health Effects of the Semipalatinsk Nuclear Test Site Activity

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Projects of Mikhail Valivach Links Russian Version

Investigation of general and reproductive health in adolescent girls in Pavlodar


Project goal: search for probable general and reproductive health effects of mercury in adolescent girls in the city of Pavlodar situated near a chemical plant.

The territory adjacent to the Pavlodar Chemical Plant, which is engaged in electrolysis production of chlorine and alkali using the mercury-pool cathode technique, has been an intense source of environmental pollution with mercury. For the period from 1975 to 1993, according to various estimates, the total mercury emission into the environment amounted to 1,394—3,021 tons. 

Pavlodar Chemical Plant
One of the goals of this study, granted by McArthurs’ Foundation, was searching for possible health impact on the residents of the city of Pavlodar situated near the plant. It was a cross-sectional study of four groups of adolescent girls (25 persons in each) living in the districts situated at different distances from the Chemical Plant. Studied parameters included mercury content in hair, physical exam, biochemical blood tests, thyroid and sexual hormones (TSH, T3 and T4, LG, FSH, estradiol, progesterone, testosterone and 17-DHA). Together with this Dr. Yuriy Rossinsky I studied psychological characteristics of the girls to compare them with hormonal status.  
Investigation of general and reproductive health in adolescent girls in Pavlodar

I have developed this study project, directed and controlled all project works, performed statistical analysis and wrote the final report. 
There were no cases of hair mercury concentration above normal. There was no dependence found of health parameters on the distance from the Chemical Plant.  Dr. Rossinskiy found significant dependence of sexual behavior in the girls on the level of androgens (testosterone and 17-DHA).

Search keywords

Pavlodar, mercury, study, research, reproduction, health, Kazakhstan.