general and reproductive health in adolescent girls in Pavlodar
Project goal: search for probable general
and reproductive health effects of mercury in adolescent girls in the
city of Pavlodar situated near a chemical plant.
territory adjacent to the Pavlodar Chemical Plant, which is engaged in
electrolysis production of chlorine and alkali using the mercury-pool
cathode technique, has been an intense source of environmental
pollution with mercury. For the period from 1975 to 1993, according to
various estimates, the total
mercury emission into the environment
amounted to 1,394—3,021 tons.
One of the goals of this study,
granted by McArthurs’ Foundation, was searching for possible
impact on the residents of the city of Pavlodar situated near the
plant. It was a cross-sectional study of four groups of adolescent
girls (25 persons in each) living in the districts situated at
different distances from the Chemical Plant. Studied parameters
included mercury content in hair, physical exam, biochemical blood
tests, thyroid and sexual hormones (TSH, T3 and T4, LG, FSH, estradiol,
progesterone, testosterone and 17-DHA). Together with this Dr. Yuriy
Rossinsky I studied psychological characteristics of the girls to
compare them with hormonal status.
I have developed this study project, directed and controlled all
project works, performed statistical analysis and wrote the final
There were no cases of hair mercury concentration above normal. There
was no dependence found of health parameters on the distance from the
Chemical Plant. Dr. Rossinskiy found significant dependence of
sexual behavior in the girls on the level of androgens (testosterone
mercury, study, research,
reproduction, health, Kazakhstan.